Cancers (Aug 2022)

The Identification and Clinical Applications of Mutated Antigens in the Era of Immunotherapy

  • Yae Kye,
  • Lokesh Nagineni,
  • Shrikanth Gadad,
  • Fabiola Ramirez,
  • Hannah Riva,
  • Lorena Fernandez,
  • Michelle Samaniego,
  • Nathan Holland,
  • Rose Yeh,
  • Kei Takigawa,
  • Subramanian Dhandayuthapani,
  • Jessica Chacon

DOI
https://doi.org/10.3390/cancers14174255
Journal volume & issue
Vol. 14, no. 17
p. 4255

Abstract

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The era of personalized cancer therapy is here. Advances in the field of immunotherapy have paved the way for the development of individualized neoantigen-based therapies that can translate into favorable treatment outcomes and fewer side effects for patients. Addressing challenges related to the identification, access, and clinical application of neoantigens is critical to accelerating the development of individualized immunotherapy for cancer patients.

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