European Journal of Breast Health (Jul 2008)
THE IMPORTANCE OF BI-RADS, AGE, AND FAMILY HISTORY DETERMINATION OF CANCER RISK IN NON-PALPABLE BREAST LESIONS
Abstract
OBJECTIVE:The increasing use of mamography in breast screening programs has resulted in the detection of large numbers of nonpalpable malignant lesions. In this study, after histopathologic results from excisional biopsies following wire localization of nonpalpable breast lesions were compared with BI-RADS, age, and family history.METHODS: Between January 2003- April 2007, 276 patients with radiologically detected suspicious lesions were enroled in this study. Wire needle localization performed with mammographically or ultrasonographicly, if lesion detected with both mammographically and ultrasonographicly, the localization was performed with ultrasonographicly. All surgical excisions were done under general anaesthesia. According to histopathological results, BI-RADS, age, and family history in patients diagnosed with malignancy were assessed statisticaly.RESULTS: The average age of patients were 47,28 ± 10,81 (range 20-79) and 167 patients (60,6%) were 50 age. Localization of suspicious lesions were performed with ultrasonographicly in 188 (62,4%) patients and mammographically in 113 (37,6) patients. There is no positive fi ndings in family history in 238 (86%) patients while 38patients (14%) determined positive history. The lesions placed into BI-RADS category in 12 patients (3,9%) BI-RADS II, 133 patients (44,2%) BI-RADS III, 135 patients (44,9%) BI-RADS IV and 21 patients (7%) BI-RADS V respectively. Probability of cancer is found 3 times more when lesion placed in BI-RADS IV and 45 times more in BI-RADS V.CONCLUSION: The lesions in BI-RADS IV and V category should be done biopsy after wire needle localization. In BI-RADS III lesions should be asessed with risk factors belongs to patients and then if necessary biopsy should be done.