Nature Communications (Jul 2023)

Prevalence of diabetic retinopathy and vision-threatening diabetic retinopathy in adults with diabetes in China

  • Xuhong Hou,
  • Limin Wang,
  • Dalong Zhu,
  • Lixin Guo,
  • Jianping Weng,
  • Mei Zhang,
  • Zhiguang Zhou,
  • Dajin Zou,
  • Qiuhe Ji,
  • Xiaohui Guo,
  • Qiang Wu,
  • Siyu Chen,
  • Rong Yu,
  • Hongli Chen,
  • Zhengjing Huang,
  • Xiao Zhang,
  • Jiarui Wu,
  • Jing Wu,
  • Weiping Jia,
  • for the China National Diabetic Chronic Complications (DiaChronic) Study Group

DOI
https://doi.org/10.1038/s41467-023-39864-w
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 11

Abstract

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Abstract The current epidemic status of diabetic retinopathy in China is unclear. A national prevalence survey of diabetic complications was conducted. 50,564 participants with gradable non-mydriatic fundus photographs were enrolled. The prevalence rates (95% confidence intervals) of diabetic retinopathy and vision-threatening diabetic retinopathy were 16.3% (15.3%–17.2%) and 3.2% (2.9%–3.5%), significantly higher in the northern than in the southern regions. The differences in prevalence between those who had not attained a given metabolic goal and those who had were more pronounced for Hemoglobin A1c than for blood pressure and low-density lipoprotein cholesterol. The participants with vision-threatening diabetic retinopathy had significantly higher proportions of visual impairment and blindness than those with non-vision-threatening diabetic retinopathy. The likelihoods of diabetic retinopathy and vision-threatening diabetic retinopathy were also associated with education levels, household income, and multiple dietary intakes. Here, we show multi-level factors associated with the presence and the severity of diabetic retinopathy.