Frontiers in Oncology (Mar 2023)

Cardiac infarction caused by PD-1 inhibitor during small cell neuroendocrine carcinoma of the ureter treatment: A case report

  • Xiaoying Li,
  • Jing Wen,
  • Hongtao Li,
  • Yan Huang,
  • Hongliang Zhou

DOI
https://doi.org/10.3389/fonc.2023.1114397
Journal volume & issue
Vol. 13

Abstract

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Although small cell neuroendocrine carcinoma of the ureter (ureteral SCNEC) is rare, it always leads to a poor prognosis. Also, no treatment recommendation has been given for ureteral SCNEC, with only PD-1/PD-L1 inhibitors being used for its treatment. Here, we report a case of atypical symptoms of cardiac infarction caused by a PD-1 inhibitor used in the treatment of ureteral SCNEC and hope to address concerns regarding the possible cardiac toxicity caused by PD-1/PD-L1 inhibitors in ureteral SCNEC patients.

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