Histological and mechanical evaluation of the osseointegration of titanium implants by the modifications of thread design and/or coating with flaxseed (An experimental study on rabbits)

Abstract

Background: Dental implant surface technologies have been evolving rapidly to enhance a more rapid bone formation on their surface and improve implant therapy.Implant threads should be designed to increase surface contact areathat induced better stability. In addition, implant surface coating with Flaxseed was used to enhance bone formation at the bone-implant interface. Materials and methods: Ninety-six commercially pure titanium (CpTi) screws were implanted in rabbits' tibiae and divided into three groups as dual-threaded group, flaxseed-coated group and control group. All groups were evaluated mechanically, histologically and radiographically after each healing periods (2, 4, 6 and 8) weeks and the resulting data were statistically analyzed using ANOVA and t-test at 0.05 significance level. Results: Dual threaded implant recorded the highest value in removal torque testand it showed mature bone at 8 weeks period. Coated implant shows enhancement of osteoblast and it is the only modified implant that illustrates proliferating cartilage zone that later on degenerated and replaced by bone. Conclusion: Each modified implants shows different benefits whether a modification of the implant surface mechanically (dual-threaded) or by coating the implants with Flaxseed.