Histopathological analysis of 2,4,5-trinitrobenzene sulphonic acid (TNBS)-induced mouse colitis

Abstract

Ulcerative colitis is one of the chronic diseases that results in inflammation of colon in humans. In this Visual experiment we demonstrate the histopathology of TNBS induced colitis model of mouse. The experiment involves following steps: a) Selection of mouse model, b) Induction of colitis, c) Paraffin sectioning of colon tissue, d) Hematoxylin and Eosin staining, and d) Microscopic observation. Video Clips 13 min 14 sec Full Screen Alternate 3 min 13 sec Full Screen Alternate

Keywords

• Colitis
• Histology
• Inflammation