The present experiment aimed to examine the impact of nano urea (NU) and plant growth-promoting rhizobacteria (PGPR) on Reshmi amaranth (Amaranthus tricolor) growth under salt stress. Experiments were conducted using six different combinations of NaCl, NU, and PGPR for 35 days under greenhouse conditions. The results showed that salinity stress significantly (p + and Ca2+ uptake. The combined NU and PGPR treatment restored ionic balance, with Na⁺ reduced to 58.12 mg and K⁺ and Ca2+ levels increasing to 115.25 mg and 78.70 mg, respectively. Stress markers such as malondialdehyde (MDA) and proline also showed significant reductions, while antioxidant enzyme activities stabilized under NU and PGPR application. Thus, this study indicated that NU and PGPR mitigate salt-induced stress by improving nutrient assimilation, promoting osmotic regulation, and enhancing antioxidative defenses in Reshmi amaranth.