516 Caspase-8 regulated senescence as an immune checkpoint in T lymphocytes for adoptive cell therapy

• Valérie Janelle,
• Mathieu Neault,
• Marie-Eve Lebel,
• Dave De Sousa,
• Salix Boulet,
• Ludovic Durrieu,
• Cedric Carli,
• Sebastien Lemieux,
• Nathalie Labrecque,
• Heather Melichar,
• Frederick Mallette,
• Jean-Sebastien Delisle

Affiliations

Valérie Janelle

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Mathieu Neault

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Marie-Eve Lebel

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Dave De Sousa

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Salix Boulet

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Ludovic Durrieu

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Cedric Carli

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Sebastien Lemieux

2Institute for Research in Immunology and Cancer, Montreal, Canada

Nathalie Labrecque

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Heather Melichar

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Frederick Mallette

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada

Jean-Sebastien Delisle

1Maisonneuve-Rosemont Hospital Research Center, Montréal, Canada