Forum of Clinical Oncology (May 2022)

Cryptosporidium and colorectal cancer: a review of epidemiology and possible association

  • Oyeyemi Oyetunde T.,
  • Oyeyemi Ifeoluwa T.,
  • Alamukii Nanfizat A.,
  • Kone Jennifer K.,
  • Oyerinde Olawunmi R.,
  • Anuoluwa Iyadunni A.,
  • Ovuakporie-uvo Oghale O.,
  • Adesina Isaac A.,
  • Oluwafemi Yinka D.,
  • Ogoanah Sylvia O.,
  • Tiamiyu Adebisi M.

DOI
https://doi.org/10.2478/fco-2021-0009
Journal volume & issue
Vol. 12, no. 3
pp. 61 – 71

Abstract

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Cryptosporidiosis is an important protozoan disease with serious public health implications. The contribution of Cryptosporidium to colorectal cancer is still vaguely studied, but little evidence from experimental and epidemiological studies has suggested a possible association. This review discusses the epidemiology of cryptosporidiosis and colorectal cancer and attempts to unravel the possible link between the two diseases using epidemiological, pathological, molecular, and immunological evidence. The review stressed the need to undertake more studies in this relatively neglected field.

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