Open Chemistry (Sep 2021)

Phytochemical profile, in vitro antioxidant, and anti-protein denaturation activities of Curcuma longa L. rhizome and leaves

  • Altir Najah Khalifah Mansour,
  • Ali Ammar Mohammed Ahmed,
  • Gaafar Abdel-Rhman Z.,
  • Qahtan Ahmed A.,
  • Abdel-Salam Eslam M.,
  • Alshameri Aref,
  • Hodhod Mohamed S.,
  • Almunqedhi Bander

DOI
https://doi.org/10.1515/chem-2021-0086
Journal volume & issue
Vol. 19, no. 1
pp. 945 – 952

Abstract

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Curcuma longa L. is a famous spice cultivated in many countries with significant variations reported in its phytochemical contents and biological potential. For the first time, the present work is aimed to identify the major phytochemicals present in methanol:chloroform (MC) and petroleum ether (PE) extracts of Curcuma longa rhizome and leaves (by determining polyphenols and GC/MS analysis), and their in-vitro antioxidant and anti-protein denaturation potential. Results showed that the highest value (P 0.5), respectively. GC/MS analysis showed that α-tumerone was the main component in the rhizome oil (32.44%), whereas in the leaf oil, palmitic acid was the prominent constituent (28.33%) and α-phellandrene recorded a comparable percentage (7.29). In conclusion, C. longa is a valuable source of natural antioxidants and anti-inflammatory constituents, as indicated by its high polyphenolic content and by its considerable in vitro antiradical and anti-protein denaturation potential.

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