International Medical Case Reports Journal (Oct 2022)
Ab Interno Goniotomy with the Kahook Dual Blade in a Monocular Patient with Mucous Membrane Pemphigoid and Refractory Open Angle Glaucoma: A Case Report
Abstract
Nefeli Eleni Kounatidou,1 Theodoros Filippopoulos,2 Sotiria Palioura3 1National and Kapodistrian University of Athens Medical School, Athens, Greece; 2Glaucoma Division, Athens Vision Eye Institute, Athens, Greece; 3Department of Ophthalmology, University of Cyprus Medical School, Nicosia, CyprusCorrespondence: Sotiria Palioura, 7 Lampsa Str, Athens, 11524, Greece, Tel +30 698 580 2355, Email [email protected]: To describe the case of a monocular patient with ocular mucous membrane pemphigoid (MMP) and open angle glaucoma refractory to medical treatment, who was successfully managed with ab interno goniotomy at the time of cataract surgery.Methods: A 63-year-old woman with a history of severe MMP presented with exacerbation of the disease in both eyes. Vision was 20/80 in the right eye and light perception in the left eye. Symblepharon formation, trichiasis and forniceal foreshortening were present in the right eye, while the cornea of the left eye was completely conjunctivalized. Following aggressive systemic immunosuppressive therapy with corticosteroids and cyclophosphamide, the disease was brought under control. However, the patient developed a mature cataract and high intraocular pressure (IOP) of 28 mmHg on maximal medical therapy. Due to the high risk of ocular MMP exacerbation with glaucoma filtration surgery, the decision was made to proceed with cataract extraction combined with ab interno goniotomy with the Kahook Dual Blade.Results: There were no intraoperative complications. The IOP has remained in the 12– 14 mmHg range without any topical glaucoma medications over a total follow up of 3.5 years.Conclusion: Ab interno goniotomy using the Kahook Dual Blade can significantly reduce IOP and medication burden in MMP cases, where any type of conjunctival incisional surgery could induce disease flare up. In this case, it represented a safe and effective surgical procedure for ocular MMP with concomitant refractory open angle glaucoma.Keywords: ocular cicatricial pemphigoid, MIGS, KDB goniotomy, phaco-KDB, ab interno goniotomy
