The clinical significance of natural autoimmunity in patients with adhesive process and external genital endometriosis

Abstract

The article presents the results of a study of 71 patients with adhesive process diagnosed with external genital endometriosis (EGE) confirmed by laparoscopy. In accordance with the specific serum immunoreactivity evaluation, all patients were divided into 3 groups: Group A (normal response type), Group B (hyper-response type) and group C (hypo-response type). The duration of infertility was on average 6,1 ± 1,3 years. After surgery patients underwent antigonadotropic therapy with 3.75 mg buserelin (a course of 4--6 injections). Against a background of the baseline therapy, all patients in groups B and C underwent correction of immunological disorders. Conclusion: Management of immunological disorders in patients with adhesive process associated with EGE enhances the effectiveness of recovery of the reproductive function

Keywords

• наружный генитальный эндометриоз
• бесплодие
• спаечный процесс
• иммунореактивность
• external genital endometriosis
• infertility
• adhesive process
• immunoreactivity