JACC: Case Reports (Jul 2025)

Transcatheter Closure of Ventricular Pseudoaneurysms Using 3D-Shaped Platinum-Based Bare-Metal Coils

  • Antonella Millin, MD,
  • Matteo Sturla, MD,
  • Andrea Scotti, MD,
  • Pan Phyu, MBBS,
  • Julio Echarte-Morales, MD,
  • Annalisa Filtz, MD,
  • Tadahisa Sugiura, MD, PhD,
  • Leandro Slipczuk, MD, PhD,
  • Edwin C. Ho, MD,
  • Azeem Latib, MD

DOI
https://doi.org/10.1016/j.jaccas.2025.103372
Journal volume & issue
Vol. 30, no. 17
p. 103372

Abstract

Read online

Ventricular pseudoaneurysms (PSAs) are contained ruptures of the ventricular wall with a high risk of rupture. Though traditionally managed with surgery, percutaneous intervention is an established option for high-risk patients. This case series is the first to evaluate the independent and combined use of large 3-dimensionally (3D) shaped platinum-based bare-metal coils for percutaneous closure of ventricular PSAs. We report on 3 patients presenting with ventricular PSAs in various locations, treated successfully with Penumbra coils alone or in combination with commonly used nitinol closure devices. While closure with a single occluder device may not always achieve complete neck sealing and isolation of the PSA, the combination with bare-metal coils has proven to be an effective and safe strategy in this context. Although these results are promising, the use of 3D-shaped platinum-based bare-metal coils remains off label for high-risk patients, highlighting the need for further research to establish standardized treatment protocols and assess long-term outcomes.

Keywords