Disorders of Lipid Metabolism and its Correction in Chronic Kidney Disease

Abstract

Chronic kidney disease — a proven risk factor of the development and progression of lipid metabolism disorders. The basis of these disorders — an increase in blood plasma cholesterol, triglycerides, low density lipoproteins and decreased levels of high density lipoproteins, apo AI and apo AII. There has been a decrease in the activity of enzymes: lipoprotein lipase, hepatic triglyceride lipase, lecithin-cholesterol acyltransferase. The use of lipid-modifying drugs — statins, fibrates, nicotinic acid was proposed.

Keywords

• chronic kidney disease
• cholesterol
• triglycerides
• low density lipoproteins
• high density lipoproteins
• apo AI
• apo AII
• lipoprotein lipase
• hepatic triglyceride lipase
• statins
• fibrates
• nicotinic acid