Emerging Infectious Diseases (Mar 2019)

Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA

  • Christopher J. Harrison,
  • William C. Weldon,
  • Barbara A. Pahud,
  • Mary Anne Jackson,
  • M. Steven Oberste,
  • Rangaraj Selvarangan

DOI
https://doi.org/10.3201/eid2503.180960
Journal volume & issue
Vol. 25, no. 3
pp. 585 – 588

Abstract

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We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012–2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected. Titers increased with age. Widespread circulation of enterovirus D68 occurred before the 2014 outbreak. Research is needed to determine a surrogate of protection.

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