Journal of Clinical Medicine (Jul 2021)
Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal Ligament
- Atsushi Kimura,
- Katsushi Takeshita,
- Toshitaka Yoshii,
- Satoru Egawa,
- Takashi Hirai,
- Kenichiro Sakai,
- Kazuo Kusano,
- Yukihiro Nakagawa,
- Kanichiro Wada,
- Keiichi Katsumi,
- Kengo Fujii,
- Takeo Furuya,
- Narihito Nagoshi,
- Tsukasa Kanchiku,
- Yukitaka Nagamoto,
- Yasushi Oshima,
- Hiroaki Nakashima,
- Kei Ando,
- Masahiko Takahata,
- Kanji Mori,
- Hideaki Nakajima,
- Kazuma Murata,
- Shunji Matsunaga,
- Takashi Kaito,
- Kei Yamada,
- Sho Kobayashi,
- Satoshi Kato,
- Tetsuro Ohba,
- Satoshi Inami,
- Shunsuke Fujibayashi,
- Hiroyuki Katoh,
- Haruo Kanno,
- Kota Watanabe,
- Shiro Imagama,
- Masao Koda,
- Yoshiharu Kawaguchi,
- Masaya Nakamura,
- Morio Matsumoto,
- Masashi Yamazaki,
- Atsushi Okawa
Affiliations
- Atsushi Kimura
- Department of Orthopedics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke 329-0498, Tochigi, Japan
- Katsushi Takeshita
- Department of Orthopedics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke 329-0498, Tochigi, Japan
- Toshitaka Yoshii
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Satoru Egawa
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Takashi Hirai
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kenichiro Sakai
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kazuo Kusano
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Yukihiro Nakagawa
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kanichiro Wada
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Keiichi Katsumi
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kengo Fujii
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Takeo Furuya
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Narihito Nagoshi
- Department of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku Ward, Tokyo 160-8582, Japan
- Tsukasa Kanchiku
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Yukitaka Nagamoto
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Yasushi Oshima
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Hiroaki Nakashima
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kei Ando
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Masahiko Takahata
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kanji Mori
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Hideaki Nakajima
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kazuma Murata
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Shunji Matsunaga
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Takashi Kaito
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kei Yamada
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Sho Kobayashi
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Satoshi Kato
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Tetsuro Ohba
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Satoshi Inami
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Shunsuke Fujibayashi
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Hiroyuki Katoh
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Haruo Kanno
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Kota Watanabe
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Shiro Imagama
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Masao Koda
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Yoshiharu Kawaguchi
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Masaya Nakamura
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Morio Matsumoto
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Masashi Yamazaki
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- Atsushi Okawa
- Japanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, Japan
- DOI
- https://doi.org/10.3390/jcm10153375
- Journal volume & issue
-
Vol. 10,
no. 15
p. 3375
Abstract
Ossification of the posterior longitudinal ligament (OPLL) is commonly associated with diabetes mellitus (DM); however, the impact of DM on cervical spine surgery for OPLL remains unclear. This study was performed to evaluate the influence of diabetes DM on the outcomes following cervical spine surgery for OPLL. In total, 478 patients with cervical OPLL who underwent surgical treatment were prospectively recruited from April 2015 to July 2017. Functional measurements were conducted at baseline and at 6 months, 1 year, and 2 years after surgery using JOA and JOACMEQ scores. The incidence of postoperative complications was categorized into early (≤30 days) and late (>30 days), depending on the time from surgery. From the initial group of 478 patients, 402 completed the 2-year follow-up and were included in the analysis. Of the 402 patients, 127 (32%) had DM as a comorbid disease. The overall incidence of postoperative complications was significantly higher in patients with DM than in patients without DM in both the early and late postoperative periods. The patients with DM had a significantly lower JOA score and JOACMEQ scores in the domains of lower extremity function and quality of life than those without DM at the 2-year follow-up.
Keywords
- ossification of the posterior longitudinal ligament
- cervical myelopathy
- diabetes mellitus
- surgical outcome
