Journal of General and Family Medicine (Sep 2023)

A patient with Marchiafava–Bignami disease type A transported by ambulance with impaired consciousness and malnutrition was successfully treated after early diagnosis by MRI

  • Yoshitaka Ooya,
  • Mayumi Ishida,
  • Nozomu Uchida,
  • Ryota Sato,
  • Akira Yoshioka,
  • Izumi Sato,
  • Hideki Onishi

DOI
https://doi.org/10.1002/jgf2.636
Journal volume & issue
Vol. 24, no. 5
pp. 303 – 306

Abstract

Read online

Abstract Marchiafava–Bignami disease (MBD) is a very rare disorder characterized by demyelination and necrosis of the corpus callosum. A 53‐year‐old male was transported to the emergency room with impaired consciousness. On his arrival, he was quite emaciated. CT examination revealed no hemorrhagic lesions whereas MR images showed hyperintense areas throughout the corpus callosum, leading to a diagnosis of MBD. His impaired consciousness improved with treatment, including parenteral thiamine administration. When examining patients with impaired consciousness because of malnutrition, MBD should be taken in consideration and the incorporation of head MR imaging into the examination protocol enables early diagnosis and treatment, and may improve the prognosis.

Keywords