Functional characteristics of serotoninergic nerves stimulating stomach and intestinal contractions

Abstract

Aim of review. To summarize the study of serotoninergic nerves stimulating the stomach and intestinal contractions. Key points. The authors established the fact that irritation of sympathetic trunk (ST) in in the chest cavity of dogs in most of the cases cause not inhibition, but rather stimulation of stomach contractions. The stimulatory effect is amplified at block of sympathetic nerve by Ornidum, and is eliminated by block of serotoninergic receptors of autonomic ganglia neurons by trimeperidine hydrochloride. It demonstrates that ST partially consists of serotoninergic nerves. Stimulatory effect for the stomach considerably exceeds brake action of sympathetic nerve. Comparative analysis of serotoninergic nerve functional properties versus sympathetic nerve was carried out. Serotoninergic nerve (as well as sympathetic) - is complex structure, that includes sympathetic trunks and their branches innervating internal organs. Conclusion. Block of serotoninergic nerve stimulation function by trimeperidine hydrochloride to our opinion may be the cause of postoperative constipation in patients who received trimeperidine hydrochloride.

Keywords

• желудок
• кишечник
• моторика
• регуляция
• серотонинергический нерв