A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein

• Sabrina Yahiya,
• Charlie N. Saunders,
• Sarah Hassan,
• Ursula Straschil,
• Oliver J. Fischer,
• Ainoa Rueda-Zubiaurre,
• Silvia Haase,
• Gema Vizcay-Barrena,
• Mufuliat Toyin Famodimu,
• Sarah Jordan,
• Michael J. Delves,
• Edward W. Tate,
• Anna Barnard,
• Matthew J. Fuchter,
• Jake Baum

Affiliations

Sabrina Yahiya

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK

Charlie N. Saunders

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK

Sarah Hassan

Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK

Ursula Straschil

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK

Oliver J. Fischer

Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK

Ainoa Rueda-Zubiaurre

Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK

Silvia Haase

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK

Gema Vizcay-Barrena

Centre for Ultrastructural Imaging, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK

Mufuliat Toyin Famodimu

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK

Sarah Jordan

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK

Michael J. Delves

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK

Edward W. Tate

Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK

Anna Barnard

Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK

Matthew J. Fuchter

Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 OBZ, UK

Jake Baum

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK