Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image

Abstract

Peripheral Nerve Sheath (PNS) tumours are rare neoplasms arising from deeper soft tissues, peripheral nerves, perineural cells, or Schwann cells with ectomesenchymal origins [1]. The incidence rate is between 4-13%, with the upper extremity being the most commonly involved site (45%) [2]. The role of Fine Needle Aspiration Cytology (FNAC), based on the cytomorphology of these neoplasms of the PNS, is challenging and often confusing, underscoring the complex diagnostic nature of the lesions. Therefore, FNAC details were highlighted by presenting a clinicopathological image and providing insight into the intricate cytomorphology involved.

Keywords

• cytomorphology
• fine needle aspiration cytology
• forearm swelling
• malignant mesenchymal tumour
• peripheral nerve sheath tumour
• soft-tissue tumour