mBio (Feb 2021)

Intracellular Density of <i>Wolbachia</i> Is Mediated by Host Autophagy and the Bacterial Cytoplasmic Incompatibility Gene <i>cifB</i> in a Cell Type-Dependent Manner in Drosophila melanogaster

  • Mark Deehan,
  • Weiwei Lin,
  • Benjamin Blum,
  • Andrew Emili,
  • Horacio Frydman

DOI
https://doi.org/10.1128/mBio.02205-20
Journal volume & issue
Vol. 12, no. 1

Abstract

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Autophagy is a eukaryotic intracellular degradation pathway which can act as an innate immune response to eliminate pathogens. Conversely, pathogens can evolve proteins which modulate the autophagy pathway to subvert degradation and establish an infection. Wolbachia