Leiomyoadenomatoid Tumor of the Uterus: Case Report and Literature Review

Abstract

Adenomatoid tumors are benign neoplasms of mesothelial origin that occur in the genital tracts of both men and women. Adenomatoid tumors are usually located in the subserosa of the cornual myometrium. They are typically small, 0.5-4 cm in diameter, but some larger and cystic adenomatoid tumors have been reported. Macroscopically, they appear as circumscribed masses, but not as sharply defined as in leiomyoma. Microscopically they consist of tubules and cords of varying sizes and shapes that are lined by flat or cuboidal epithelial cells. The microscopic appearance may mimic a malignant tumor due to irregular pseudoinfiltration with tubular formations that suggest presence of an infiltrating carcinoma into a leiomyoma or the myometrium. In this paper we report a very rare case of a leiomyoadenomatoid tumor of the uterus with emphasis on the morphologic and immunohistochemical findings, and discuss the differential diagnosis with review of the recent literature.

Keywords

• adenomatoid tumor
• immunohistochemistry
• uterus