Cephalalgia Reports (Feb 2022)

Tolosa-Hunt syndrome after COVID-19 infection

  • Tyler Etheridge,
  • Jordan Jones,
  • Eric L Caskey,
  • Kathleen B Digre,
  • Judith EA Warner,
  • Meagan D Seay

DOI
https://doi.org/10.1177/25158163221078977
Journal volume & issue
Vol. 5

Abstract

Read online

Tolosa-Hunt syndrome (THS) is a rare, idiopathic, non-specific inflammation within the cavernous sinus and/or superior orbital fissure leading to painful ophthalmoplegia. The authors describe the first case of a 12-year-old otherwise healthy girl who presented with painful ophthalmoplegia after a documented COVID-19 infection. Neuroimaging revealed inflammation within the ipsilateral cavernous sinus, Meckel’s cave, and orbital apex. After a comprehensive work-up was negative, the patient experienced prompt clinical and radiographic improvement with high-dose corticosteroids, and a diagnosis of THS was made.