International Journal Bioautomation (Dec 2019)

Study on Biological Activity of Pinus Armandi Franch Seed Oil

  • Jianxia Guo,
  • Fang Chen,
  • Jixia Ren,
  • Xue Wen

DOI
https://doi.org/10.7546/ijba.2019.23.4.000742
Journal volume & issue
Vol. 23, no. 4
pp. 511 – 520

Abstract

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Pinus armandi franch is a unique specialty plant in China and its seed oil can be a nice resource of linoleic acid (LA) with a content of 63% of the total fatty acid. LA has many pharmaceutical applications and the absence of LA in the diet is chargeable for the generation and the development of different anomalous diseases. The hypolipidemic effect of Pinus armandi franch seed oil (PAFO) was studied in the work. Fifty rats were involved in the study with ten rats in each group. One group is normal, whereas the others were hypercholesterolemic. Hypolipidemic effects were investigated in both plasma and tissues. After 42 days of feeding, the arteriosclerosis index (AI) decreased by administration of PAFO in comparison with the control group fed with high-fat diet. In both normal and hypercholesterolemic condition plasma cholesterol, low-density lipoprotein, and triacylglycerols were reduced by feeding the rats with PAFO. However, the high-density lipoprotein levels increased with the administration of PAFO. It demonstrated PAFO could clear up cholesterol that could form deposits in the artery walls, promote fat metabolism, prevent metabolic disorders of lipoproteins.

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