Asymptomatic Solitary Mastocytoma with Negative Darier’s Sign

Abstract

Mastocytosis is a heterogenous group of disorders characterised by clonal proliferation of mast cells accumulating in single or multiple organs in children or adults. Skin is the most common organ involved in children. It usually presents as a nodule or plaque, yellow to tan-brown in colour remaining asymptomatic or may become red and itchy on rubbing indicating Darier’s sign positivity which helps in clinical diagnosis of mastocytosis. This case is of a three-month-old baby who presented with solitary asymptomatic noduloplaque with negative Darier’s sign which was clinically suspected to be mastocytosis and was confirmed by histopathology and immunohistochemistry.

Keywords

• good prognosis
• noduloplaque
• non-itchy
• paediatric mastocytosis