Nature Communications (Jul 2021)
Development and implementation of a scalable and versatile test for COVID-19 diagnostics in rural communities
- A. Ceci,
- C. Muñoz-Ballester,
- A. N. Tegge,
- K. L. Brown,
- R. A. Umans,
- F. M. Michel,
- D. Patel,
- B. Tewari,
- J. Martin,
- O. Alcoreza,
- T. Maynard,
- D. Martinez-Martinez,
- P. Bordwine,
- N. Bissell,
- M. J. Friedlander,
- H. Sontheimer,
- C. V. Finkielstein
Affiliations
- A. Ceci
- Molecular Diagnostics Laboratory, Fralin Biomedical Research Institute, Virginia Tech
- C. Muñoz-Ballester
- Center for Glial Biology in Health, Disease, and Cancer, Fralin Biomedical Research Institute at VTC
- A. N. Tegge
- Department of Statistics, Virginia Tech
- K. L. Brown
- Virginia Tech Carilion School of Medicine
- R. A. Umans
- Center for Glial Biology in Health, Disease, and Cancer, Fralin Biomedical Research Institute at VTC
- F. M. Michel
- Department of Geosciences, Virginia Tech
- D. Patel
- Center for Glial Biology in Health, Disease, and Cancer, Fralin Biomedical Research Institute at VTC
- B. Tewari
- Center for Glial Biology in Health, Disease, and Cancer, Fralin Biomedical Research Institute at VTC
- J. Martin
- Center for Glial Biology in Health, Disease, and Cancer, Fralin Biomedical Research Institute at VTC
- O. Alcoreza
- Center for Glial Biology in Health, Disease, and Cancer, Fralin Biomedical Research Institute at VTC
- T. Maynard
- Fralin Biomedical Research Institute at VTC
- D. Martinez-Martinez
- MRC London Institute of Medical Sciences
- P. Bordwine
- Division of Surveillance and Investigation, Office of Epidemiology, Virginia Department of Health
- N. Bissell
- New River Valley Health District, Virginia Department of Health
- M. J. Friedlander
- Fralin Biomedical Research Institute at VTC
- H. Sontheimer
- Center for Glial Biology in Health, Disease, and Cancer, Fralin Biomedical Research Institute at VTC
- C. V. Finkielstein
- Molecular Diagnostics Laboratory, Fralin Biomedical Research Institute, Virginia Tech
- DOI
- https://doi.org/10.1038/s41467-021-24552-4
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 14
Abstract
Here, the authors report the development of a versatile academic, SARSCoV-2 RT-qPCR molecular diagnostic test that uses 3D printed technology for sample collection, is implemented in rural setting in the US state of Virginia and validated in its population.