Dissemination of Ras V12 -transformed cells requires the mechanosensitive channel Piezo

Abstract

Drosophila tumours can be utilised to study the mechanisms of cell dissemination. Here, the authors use Drosophila midgut to examine the course of Ras V12 -transformed cell dissemination from midgut into circulation, which requires the actions of invasive protrusions and the mechanosensitive channel Piezo.