Respiratory Medicine Case Reports (Jan 2020)

Bronchial HPV; the good the bad and the unknown

  • Paul Zarogoulidis,
  • Stavros Tryfon,
  • Konstantinos Sapalidis,
  • Kosmas Tsakiridis,
  • Sofia Baka,
  • Haidong Huang,
  • Chong Bai,
  • Wolfgang Hohenforst-Schmidt,
  • Dimitris Hatzibougias,
  • Evaggelia Athanasiou,
  • Anastasios Vagionas,
  • Maria Saroglou,
  • Christoforos Kosmidis

Journal volume & issue
Vol. 30
p. 101053

Abstract

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Background: Solitary tracheobronchial papilloma (STBP) is a rare benign tumor. Human papilloma virus (HPV) infection is associated with dysplasia and a high risk of carcinoma. Case 1: Sixty five year old male with hemoptysis and with coilocytic atypia, indicating the presence of HPV. Case 2: Thirty two year old female with a polypoid villoglandular bronchial structure and no cytoplasmic or nuclear atypia but prominent microvilli. Discussion: Tissue sample is the best sample in order to determine and distinguish the two entities, local treatment should be considered as first option when possible.

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