A study of scrub typhus cases from a tertiary care hospital in Dehradun

Indian Journal of Community Health. 2015;27(1):150-154


Journal Homepage

Journal Title: Indian Journal of Community Health

ISSN: 0971-7587 (Print); 2248-9509 (Online)

Publisher: Indian Association of Preventive and Social Medicine, Uttar Pradesh & Uttarakhand

Society/Institution: Indian Association of Preventive and Social Medicine

LCC Subject Category: Medicine: Public aspects of medicine

Country of publisher: India

Language of fulltext: English

Full-text formats available: PDF, HTML



Megha Luthra (SGRRIM&HS, Dehradun, Uttarakhand)
Amit Varma (SGRRIM&HS, Dehradun, Uttarakhand)
Sudhir Kumar Gupta (SGRRIM&HS, Dehradun, Uttarakhand)
Kamal Singh Negi (SGRRIM&HS, Dehradun, Uttarakhand)


Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 10 weeks


Abstract | Full Text

<p><strong>Introduction:</strong> Scrub Typhus is a trombiculid mite-borne rickettsial zoonosis caused by Orientia tsutsugamushi, which is widely endemic in the Asia–Pacific region and threatens a population of millions. Aim and <strong>Objectives:</strong> To study epidemiology and clinical profile of Scrub Typhus Cases in a clinical setting and to clarify current diagnostic issues of scrub typhus. <strong>Materials and methods</strong>: Study period was August to December 2014. 197 clinical cases confirmed by positive result in immunoglobulin (IgG, IgM or IgA) using a rapid immuno-chromatographic assay (Bioline SD Tsutsugamushi One Step Scrub typhus Antibody test) were included. <strong>Results:</strong> 27.4% cases were in the age group of 20-30 years followed by cases in the age group of 10-20 as well as 40-50 years (15.7%). More than half of all the cases were female (58.4%). 29.9% were still studying and and 17.8% were illiterate/just literate. 29.4% cases were from district Dehradun followed by cases from district Saharanpur (25.4%). Most cases were not working, i.e. were housewives (42.6%) followed by students (29.9%). Most common presenting features were fever with gastro-intestinal symptoms (51.3%). All the cases were treated with appropriate antibiotics (Doxycycline, Azithromycin and a higher generation cephalosporin for secondary complications). 38.1% cases went on to develop a complication during their hospital stay. All were discharged in satisfactory condition except for two mortalities during the study period</p>