International Journal of Fertility and Sterility (Jan 2024)

Validity and Reliability of The Persian Version of Uterine Fibroid Symptom and Health-Related Quality of Life Questionnaire: A Psychometric Study

  • Hanieh Najafiarab,
  • Amirreza Keyvanfar,
  • Farima Rahimi Mansour,
  • Hamidreza Didar,
  • Shaghayegh Hooshmand Chayijan,
  • Shahrzad Rajaei Firouzabadi,
  • Maryam Sadat Hosseini,
  • Zahra Bakhtiyari,
  • Farah Farzaneh

DOI
https://doi.org/10.22074/ijfs.2023.1988864.1431
Journal volume & issue
Vol. 18, no. 1
pp. 60 – 66

Abstract

Read online

Background: Women with uterine fibroids (UFs) experience many clinical manifestations that affect their quality oflife (QOL). The Uterine Fibroid Symptom and Health-related Quality of Life (UFS-QOL) questionnaire is an Englishinstrument specifically designed to assess fibroid-related symptoms and their impact on QOL. This study aims toinvestigate the reliability and validity of the Persian version of the UFS-QOL questionnaire in Iranian women with UF.Materials and Methods: In this psychometric study, women with UFs who presented to Imam Hossein Hospital(Tehran, Iran) between August 2022 and January 2023 were enrolled in this study. A forward-backward approachwas applied to translate the UFS-QOL questionnaire into Persian. The reliability of the UFS-QOL questionnaire wasassessed by internal consistency and test-retest correlation. Confirmatory factor analysis (CFA) was used to assessconvergent validity between items and subscales of the UFS-QOL questionnaire. Pearson’s correlation coefficient wasused to assess convergence validity between subscales of the UFS-QOL and the World Health Organization Qualityof Life Brief Version 26 questionnaire (WHOQOL-BREF-26).Results: Overall, we assessed 226 women with UFs. All subscales of the UFS-QOL questionnaire had acceptableinternal consistency (Cronbach’s alpha>0.7). Test-retest analysis indicated significant positive correlations betweentwo measurements of all subscales of the UFS-QOL questionnaire: symptom severity (P<0.001), concern (P<0.001),activities (P<0.001), energy/mood (P<0.001), control (P<0.001), self-consciousness (P=0.002), and sexual function(P<0.001). The Kaiser-Meyer-Olkin (KMO) measure value was 0.920, and the result of Bartlett’s test of sphericitywas significant (P<0.001). CFA identified six factors for the health-related QOL (HRQL) questionnaire, which explained73.827% of the total variation. Most subscales of the UFS-QOL questionnaire correlated with domains of theWHOQOL-BREF-26 questionnaire (P<0.05).Conclusion: The Persian version of the UFS-QOL questionnaire is a valid and reliable instrument to evaluate UFrelatedsymptoms and QOL among Iranian women.

Keywords