Архивъ внутренней медицины (May 2022)

Gastroesophageal Reflux Disease: Diagnosis, Medication, Balneotherapy

  • A. E. Shklyaev,
  • V. M. Dudarev

DOI
https://doi.org/10.20514/2226-6704-2022-12-3-195-202
Journal volume & issue
Vol. 12, no. 3
pp. 195 – 202

Abstract

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The article presents modern views on the problem of gastroesophageal reflux disease (GERD). Data on the prevalence and risk factors for the development of the disease are presented. Emphasis is placed on the special role of slightly acidic and slightly alkaline reflux in the pathogenesis of GERD, which, in combination with dysfunction of the lower esophageal sphincter and impaired motor-evacuation function of the stomach, are important factors, determining the the lack of effectiveness of standard antisecretory therapy. The exceptional importance of the 24-hour pH impedanceometry method is emphasized for the differential diagnosis of the non-erosive form of GERD with functional heartburn and hypersensitivity of the esophagus to reflux (the so-called hypersensitive esophagus). The data of the results of domestic and foreign studies devoted to the evaluation of the effectiveness of the use of physiotherapeutic methods and drinking balneotherapy in patients with GERD are given.

Keywords