GPA-Induced Granulomatous Endocarditis Mimicking a Thrombotic Mitral Valve Stenosis

Christoph Marquetand, MD; Peter Lamprecht, MD; Franz F. Dressler, MD; Sven Perner, MD, PhD; Konstanze Holl-Ulrich, MD; Ulrich Stierle, MD; Anas Aboud, MD; Jan-Christian Reil, MD

JACC: Case Reports (Nov 2020)

GPA-Induced Granulomatous Endocarditis Mimicking a Thrombotic Mitral Valve Stenosis

Christoph Marquetand, MD,
Peter Lamprecht, MD,
Franz F. Dressler, MD,
Sven Perner, MD, PhD,
Konstanze Holl-Ulrich, MD,
Ulrich Stierle, MD,
Anas Aboud, MD,
Jan-Christian Reil, MD

Affiliations

Christoph Marquetand, MD: Department of Cardiology, Angiology and Intensive Care, Medical Clinic II, University Heart Center Lübeck, Lübeck, Germany; Address for correspondence: Dr. Christoph Marquetand, Department of Cardiology, Angiology and Intensive Care Medicine, University Heart Center Luebeck, University Hospital Schleswig-Holstein, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Peter Lamprecht, MD: Department of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany
Franz F. Dressler, MD: Institute of Pathology, University Hospital Schleswig-Holstein, Lübeck, Germany
Sven Perner, MD, PhD: Institute of Pathology, University Hospital Schleswig-Holstein, Lübeck, Germany; Pathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany
Konstanze Holl-Ulrich, MD: Pathology Hamburg, MVZ Labor Lademannbogen GmbH, Hamburg, Germany
Ulrich Stierle, MD: Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig-Holstein, Campus Lübeck, Lübeck, Germany
Anas Aboud, MD: Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig-Holstein, Campus Lübeck, Lübeck, Germany
Jan-Christian Reil, MD: Department of Cardiology, Angiology and Intensive Care, Medical Clinic II, University Heart Center Lübeck, Lübeck, Germany

Journal volume & issue: Vol. 2, no. 14
pp. 2151 – 2155

Abstract

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We present the case of a patient with granulomatous endocarditis of the mitral valve leading to severe valve stenosis caused by granulomatosis with polyangiitis. Endocarditis is a rare complication of granulomatosis with polyangiitis that may be misdiagnosed as infectious endocarditis or, as in our case, thrombotic lesions. (Level of Difficulty: Intermediate.)

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

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Abstract

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