Fast raster-scan optoacoustic mesoscopy enables assessment of human melanoma microvasculature in vivo

Hailong He; Christine Schönmann; Mathias Schwarz; Benedikt Hindelang; Andrei Berezhnoi; Susanne Annette Steimle-Grauer; Ulf Darsow; Juan Aguirre; Vasilis Ntziachristos

doi:10.1038/s41467-022-30471-9

Nature Communications (May 2022)

Fast raster-scan optoacoustic mesoscopy enables assessment of human melanoma microvasculature in vivo

Hailong He,
Christine Schönmann,
Mathias Schwarz,
Benedikt Hindelang,
Andrei Berezhnoi,
Susanne Annette Steimle-Grauer,
Ulf Darsow,
Juan Aguirre,
Vasilis Ntziachristos

Affiliations

Hailong He: Institute of Biological and Medical Imaging, Helmholtz Zentrum München
Christine Schönmann: Department of Dermatology and Allergy, Technical University of Munich
Mathias Schwarz: iThera Medical GmbH
Benedikt Hindelang: Department of Dermatology and Allergy, Technical University of Munich
Andrei Berezhnoi: Institute of Biological and Medical Imaging, Helmholtz Zentrum München
Susanne Annette Steimle-Grauer: Department of Dermatology and Allergy, Technical University of Munich
Ulf Darsow: Department of Dermatology and Allergy, Technical University of Munich
Juan Aguirre: Institute of Biological and Medical Imaging, Helmholtz Zentrum München
Vasilis Ntziachristos: Institute of Biological and Medical Imaging, Helmholtz Zentrum München

DOI: https://doi.org/10.1038/s41467-022-30471-9
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 10

Abstract

Read online

Raster-Scanning-Optoacoustic Mesoscopy can be used to image the vasculature in skin cancer lesions but is limited by a long exposure time. Here; the authors increase the speed of the imaging using co-axial illumination and a high-sensitivity ultrasound detector path.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal