Can Mean Platelet Volume and Platelet Distribution Width Predict Readmissions Within 24 Hours to Emergency Department?

Abstract

INTRODUCTION: In this study; We aimed to investigate the relationship between Mean Platelet Volume(MPV) and Platelet Distribution Width(PDW) values obtained from the initial hemogram of the patients admitted to the emergency department with the re-admission rate to the emergency department within the first 24 hours after discharge. METHODS: This retrospective case-control study was conducted with patients that presented to the emergency service over a year. The patients were divided into two groups: The first consisted of patients who, after presenting to the emergency department and being discharged, were readmitted to the same service within the first 24 hours, second group comprised those that were not re-admitted to the emergency department within this period. Statistical analysis was performed between the groups and the ability of these parameters to predict re-admission. A p value of <0.05 was considered statistically significant. RESULTS: The study was carried out with 614 cases consisting of 216 patients in the readmission group and 398 patients in the control group. When the differences between the groups in terms of hemogram parameters were examined, it was determined that MPV and PDW were higher in the readmission group compared to the control group. The multivariate regression analysis revealed that MPV and PDW were significant predictors of readmission cases. According to the ROC curve analysis, MPV had 90.2% sensitivity and 22.5% specificity while for PDW, these values were 20% and 77.0%. DISCUSSION AND CONCLUSION: It was concluded that MPV and PDW could be guiding parameters in predicting cases of emergency department readmission within 24 hours of discharge.

Keywords

• patient readmission
• mean platelet volume
• platelet distribution width
• platelets