Italian Journal of Pediatrics (Mar 2024)

Exercise-induced bronchoconstriction, allergy and sports in children

  • Angela Klain,
  • Mattia Giovannini,
  • Luca Pecoraro,
  • Simona Barni,
  • Francesca Mori,
  • Lucia Liotti,
  • Carla Mastrorilli,
  • Francesca Saretta,
  • Riccardo Castagnoli,
  • Stefania Arasi,
  • Lucia Caminiti,
  • Mariannita Gelsomino,
  • Cristiana Indolfi,
  • Michele Miraglia del Giudice,
  • Elio Novembre

DOI
https://doi.org/10.1186/s13052-024-01594-0
Journal volume & issue
Vol. 50, no. 1
pp. 1 – 11

Abstract

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Abstract Exercise-induced bronchoconstriction (EIB) is characterized by the narrowing of airways during or after physical activity, leading to symptoms such as wheezing, coughing, and shortness of breath. Distinguishing between EIB and exercise-induced asthma (EIA) is essential, given their divergent therapeutic and prognostic considerations. EIB has been increasingly recognized as a significant concern in pediatric athletes. Moreover, studies indicate a noteworthy prevalence of EIB in children with atopic predispositions, unveiling a potential link between allergic sensitivities and exercise-induced respiratory symptoms, underpinned by an inflammatory reaction caused by mechanical, environmental, and genetic factors. Holistic management of EIB in children necessitates a correct diagnosis and a combination of pharmacological and non-pharmacological interventions. This review delves into the latest evidence concerning EIB in the pediatric population, exploring its associations with atopy and sports, and emphasizing the appropriate diagnostic and therapeutic approaches by highlighting various clinical scenarios.

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