Haematologica (Sep 2007)

Role of ozone therapy in the treatment of osteonecrosis of the jaws in multiple myeloma patients

  • Maria Teresa Petrucci,
  • Cristiano Gallucci,
  • Alessandro Agrillo,
  • Maria Cristina Mustazza,
  • Robin Fo

DOI
https://doi.org/10.3324/haematol.11096
Journal volume & issue
Vol. 92, no. 9

Abstract

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Current treatments for bisphosphonate-associated osteonecrosis of the jaw (ONJ) in multiple myeloma patients have limited efficacy. The biological effects of ozone indicate it may be therapeutic for ONJ. We, here, report the efficacy of a 15-day course of antibiotics, surgery and ozone therapy in 12 MM patients with ONJ.