Dermoscopic aid in diagnosing vulval intraepithelial neoplasia

Abstract

Vulval intraepithelial neoplasia (VIN) is a premalignant disease which has the propensity to progress to vulval squamous cell carcinoma. Usual type of VIN is commonly seen in young female patients associated with human papillomavirus (HPV) infection. In this case report, a 50-year-old postmenopausal woman presents with an asymptomatic lesion over vulva since 5 years. Dermoscopic evaluation of the lesion showed the presence of finger-like, knob–like, and mosaic patterns with glomerular and dotted vessels as vascular pattern. The histopathological examination showed the presence of cells with atypical vesicular nuclei in basal and parabasal layer of epidermis and koilocytes. The diagnosis of usual type of VIN induced by HPV was made in a postmenopausal woman, which is a rare entity.

Keywords

• dermoscopy
• histopathology
• usual type vulval intraepithelial neoplasia
• vulval intraepithelial neoplasia