Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease

• Marita Westhrin,
• Siv Helen Moen,
• Toril Holien,
• Anne Kærsgaard Mylin,
• Lene Heickendorff,
• Oddrun Elise Olsen,
• Anders Sundan,
• Ingemar Turesson,
• Peter Gimsing,
• Anders Waage,
• Therese Standal

Affiliations

Marita Westhrin

K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

Siv Helen Moen

K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

Toril Holien

K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

Anne Kærsgaard Mylin

Department of Haematology, Rigshospitalet, University of Copenhagen, Denmark

Lene Heickendorff

Department of Clinical Biochemistry, Aarhus University Hospital, Denmark

Oddrun Elise Olsen

K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

Anders Sundan

K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

Ingemar Turesson

Department of Hematology, Skane University Hospital, Malmo, Sweden

Peter Gimsing

Department of Haematology, Rigshospitalet, University of Copenhagen, Denmark

Anders Waage

K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

Therese Standal

K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway;Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway