Communications Biology (Jun 2021)

Building a stem cell-based primate uterus

  • Sophie Bergmann,
  • Magdalena Schindler,
  • Clara Munger,
  • Christopher A. Penfold,
  • Thorsten E. Boroviak

DOI
https://doi.org/10.1038/s42003-021-02233-8
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 12

Abstract

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Bergmann et al. discuss the construction of synthetic uteri to model the earliest stages of human embryogenesis and associated pathologies. They highlight the constituent components from which a synthetic uterus may be engineered, propose a modular approach to assembling synthetic uteri and discuss how these technologies can shed light on implantation failure and uterine pathologies.