Constructing 3D interaction maps from 1D epigenomes

Yun Zhu; Zhao Chen; Kai Zhang; Mengchi Wang; David Medovoy; John W. Whitaker; Bo Ding; Nan Li; Lina Zheng; Wei Wang

doi:10.1038/ncomms10812

Nature Communications (Mar 2016)

Constructing 3D interaction maps from 1D epigenomes

Yun Zhu,
Zhao Chen,
Kai Zhang,
Mengchi Wang,
David Medovoy,
John W. Whitaker,
Bo Ding,
Nan Li,
Lina Zheng,
Wei Wang

Affiliations

Yun Zhu: Department of Chemistry and Biochemistry, University of California at San Diego
Zhao Chen: Department of Chemistry and Biochemistry, University of California at San Diego
Kai Zhang: Department of Chemistry and Biochemistry, University of California at San Diego
Mengchi Wang: Department of Chemistry and Biochemistry, University of California at San Diego
David Medovoy: Department of Chemistry and Biochemistry, University of California at San Diego
John W. Whitaker: Department of Chemistry and Biochemistry, University of California at San Diego
Bo Ding: Department of Chemistry and Biochemistry, University of California at San Diego
Nan Li: Department of Chemistry and Biochemistry, University of California at San Diego
Lina Zheng: Department of Chemistry and Biochemistry, University of California at San Diego
Wei Wang: Department of Chemistry and Biochemistry, University of California at San Diego

DOI: https://doi.org/10.1038/ncomms10812
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 11

Abstract

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The human genome is highly organized, with one-dimensional chromatin states packaged into higher level three-dimensional architecture. Here, the authors present EpiTensor that can identify 3D spatial associations from 1D epigenetic information.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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