mBio (Feb 2021)
Genome Sequencing of Sewage Detects Regionally Prevalent SARS-CoV-2 Variants
- Alexander Crits-Christoph,
- Rose S. Kantor,
- Matthew R. Olm,
- Oscar N. Whitney,
- Basem Al-Shayeb,
- Yue Clare Lou,
- Avi Flamholz,
- Lauren C. Kennedy,
- Hannah Greenwald,
- Adrian Hinkle,
- Jonathan Hetzel,
- Sara Spitzer,
- Jeffery Koble,
- Asako Tan,
- Fred Hyde,
- Gary Schroth,
- Scott Kuersten,
- Jillian F. Banfield,
- Kara L. Nelson
Affiliations
- Alexander Crits-Christoph
- Department of Plant and Microbial Biology, University of California, Berkeley, California, USA
- Rose S. Kantor
- Department of Civil and Environmental Engineering, University of California, Berkeley, California, USA
- Matthew R. Olm
- Department of Microbiology and Immunology, Stanford University, Stanford, California, USA
- Oscar N. Whitney
- Department of Molecular and Cell Biology, University of California, Berkeley, California, USA
- Basem Al-Shayeb
- Department of Plant and Microbial Biology, University of California, Berkeley, California, USA
- Yue Clare Lou
- Department of Plant and Microbial Biology, University of California, Berkeley, California, USA
- Avi Flamholz
- Department of Molecular and Cell Biology, University of California, Berkeley, California, USA
- Lauren C. Kennedy
- Department of Civil and Environmental Engineering, University of California, Berkeley, California, USA
- Hannah Greenwald
- Department of Civil and Environmental Engineering, University of California, Berkeley, California, USA
- Adrian Hinkle
- Department of Civil and Environmental Engineering, University of California, Berkeley, California, USA
- Jonathan Hetzel
- Illumina, San Diego, California, USA
- Sara Spitzer
- Illumina, San Diego, California, USA
- Jeffery Koble
- Illumina, San Diego, California, USA
- Asako Tan
- Illumina, San Diego, California, USA
- Fred Hyde
- Illumina, Madison, Wisconsin, USA
- Gary Schroth
- Illumina, San Diego, California, USA
- Scott Kuersten
- Illumina, Madison, Wisconsin, USA
- Jillian F. Banfield
- Innovative Genomics Institute, Berkeley, California, USA
- Kara L. Nelson
- Innovative Genomics Institute, Berkeley, California, USA
- DOI
- https://doi.org/10.1128/mBio.02703-20
- Journal volume & issue
-
Vol. 12,
no. 1
Abstract
Viral genome sequencing has guided our understanding of the spread and extent of genetic diversity of SARS-CoV-2 during the COVID-19 pandemic. SARS-CoV-2 viral genomes are usually sequenced from nasopharyngeal swabs of individual patients to track viral spread.