mBio (Feb 2021)

Genome Sequencing of Sewage Detects Regionally Prevalent SARS-CoV-2 Variants

  • Alexander Crits-Christoph,
  • Rose S. Kantor,
  • Matthew R. Olm,
  • Oscar N. Whitney,
  • Basem Al-Shayeb,
  • Yue Clare Lou,
  • Avi Flamholz,
  • Lauren C. Kennedy,
  • Hannah Greenwald,
  • Adrian Hinkle,
  • Jonathan Hetzel,
  • Sara Spitzer,
  • Jeffery Koble,
  • Asako Tan,
  • Fred Hyde,
  • Gary Schroth,
  • Scott Kuersten,
  • Jillian F. Banfield,
  • Kara L. Nelson

DOI
https://doi.org/10.1128/mBio.02703-20
Journal volume & issue
Vol. 12, no. 1

Abstract

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Viral genome sequencing has guided our understanding of the spread and extent of genetic diversity of SARS-CoV-2 during the COVID-19 pandemic. SARS-CoV-2 viral genomes are usually sequenced from nasopharyngeal swabs of individual patients to track viral spread.