European Thyroid Journal (Jan 2023)

2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid carcinoma

  • Chantal A Lebbink,
  • Agnieszka Czarniecka,
  • Renuka P Dias,
  • Rossella Elisei,
  • Louise Izatt,
  • Heiko Krude,
  • Kerstin Lorenz,
  • Markus Luster,
  • Kate Newbold,
  • Arnoldo Piccardo,
  • Manuel Sobrinho-Simões,
  • Toru Takano,
  • A S Paul van Trotsenburg,
  • Frederik A Verburg,
  • Hanneke M van Santen,
  • Thera P Links

DOI
https://doi.org/10.1530/ETJ-22-0146
Journal volume & issue
Vol. 11, no. 6
pp. 1 – 40

Abstract

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At present, no European recommendations for the management of pediatric thyroid nodules and differentiated thyroid carcinoma (DTC) exist. Differe nces in clinical, molecular, and pathological characteristics between pediatric and adult DTC emphasize the need for specific recommendations for the pediatric populati on. An expert panel was instituted by the executive committee of the European Thyroid Association including an international community of experts from a variety of disciplines including pediatric and adult endocrinology, pathology, endocrine surgery, nuclear medicine, clinical genetics, and oncology. The 2015 American Thyroid Association Pediatric Guideline was used as framework for the present guideline. Areas of discordance were identified, and clinical questions were formulated. The expert panel members discussed the evidence and formulated recommendations based on the latest evidence and expert opinion. Children with a thyroid nodule or DTC require expert care in an experienced center. The present guideline provides guidance for healthcare professionals to make well-considered decisions together with patients and parents regarding diagnosis, treatment, and follow-up of pediatric thyroid nodules and DTC.

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