Endocrine Regulations (Jan 2020)

Chronic exposure of adult male Wistar rats to bisphenol A causes testicular oxidative stress: Role of gallic acid

  • Olukole Samuel Gbadebo,
  • Ola-Davies Eunice Olufunke,
  • Lanipekun Damilare Olaniyi,
  • Oke Bankole Olusiji

DOI
https://doi.org/10.2478/enr-2020-0003
Journal volume & issue
Vol. 54, no. 1
pp. 14 – 21

Abstract

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Objectives. Bisphenol A (BPA) has been reported that among other male reproductive dys-functions, it can cause marked estrogenic effects including alteration in serum hormones as well as testicular lesions in exposed animals. This work sought to study the role of gallic acid (GA), a known antioxidant, on the BPA-induced testicular oxidative stress in adult male Wistar rats using serum hormone analysis, histopathology, and biochemical assays.

Keywords