High titre neutralizing antibodies in response to SARS–CoV–2 infection require RBD–specific CD4 T cells that include proliferative memory cells

• Chansavath Phetsouphanh,
• Weng Hua Khoo,
• Weng Hua Khoo,
• Katherine Jackson,
• Vera Klemm,
• Annett Howe,
• Anupriya Aggarwal,
• Anouschka Akerman,
• Vanessa Milogiannakis,
• Alberto Ospina Stella,
• Romain Rouet,
• Peter Schofield,
• Megan L. Faulks,
• Hannah Law,
• Thidarat Danwilai,
• Mitchell Starr,
• C. Mee Ling Munier,
• Daniel Christ,
• Mandeep Singh,
• Mandeep Singh,
• Peter I. Croucher,
• Fabienne Brilot-Turville,
• Fabienne Brilot-Turville,
• Stuart Turville,
• Tri Giang Phan,
• Tri Giang Phan,
• Gregory J. Dore,
• Gregory J. Dore,
• David Darley,
• Philip Cunningham,
• Gail V. Matthews,
• Gail V. Matthews,
• Anthony D. Kelleher,
• Anthony D. Kelleher,
• John J. Zaunders

Affiliations

Chansavath Phetsouphanh

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Weng Hua Khoo

Garvan Institute of Medical Research, Sydney, NSW, Australia

Weng Hua Khoo

St. Vincent’s Clinical School, Faculty of Medicine, University of New South Wales (UNSW) Sydney, Sydney, NSW, Australia

Katherine Jackson

Garvan Institute of Medical Research, Sydney, NSW, Australia

Vera Klemm

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Annett Howe

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Anupriya Aggarwal

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Anouschka Akerman

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Vanessa Milogiannakis

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Alberto Ospina Stella

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Romain Rouet

Garvan Institute of Medical Research, Sydney, NSW, Australia

Peter Schofield

Garvan Institute of Medical Research, Sydney, NSW, Australia

Megan L. Faulks

Garvan Institute of Medical Research, Sydney, NSW, Australia

Hannah Law

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Thidarat Danwilai

NSW State Reference Laboratory for HIV, St. Vincent’s Centre for Applied Medical Research, Sydney, NSW, Australia

Mitchell Starr

NSW State Reference Laboratory for HIV, St. Vincent’s Centre for Applied Medical Research, Sydney, NSW, Australia

C. Mee Ling Munier

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Daniel Christ

Garvan Institute of Medical Research, Sydney, NSW, Australia

Mandeep Singh

Garvan Institute of Medical Research, Sydney, NSW, Australia

Mandeep Singh

St. Vincent’s Clinical School, Faculty of Medicine, University of New South Wales (UNSW) Sydney, Sydney, NSW, Australia

Peter I. Croucher

Garvan Institute of Medical Research, Sydney, NSW, Australia

Fabienne Brilot-Turville

Brain and Mind Centre, Children’s Hospital at Westmead, University of Sydney, Sydney, NSW, Australia

Fabienne Brilot-Turville

Sydney Institute for Infectious Diseases, The University of Sydney, Sydney, NSW, Australia

Stuart Turville

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Tri Giang Phan

Garvan Institute of Medical Research, Sydney, NSW, Australia

Tri Giang Phan

St. Vincent’s Clinical School, Faculty of Medicine, University of New South Wales (UNSW) Sydney, Sydney, NSW, Australia

Gregory J. Dore

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Gregory J. Dore

Department of Infectious Diseases, St. Vincent's Hospital, Sydney, NSW, Australia

David Darley

Department of Infectious Diseases, St. Vincent's Hospital, Sydney, NSW, Australia

Philip Cunningham

NSW State Reference Laboratory for HIV, St. Vincent’s Centre for Applied Medical Research, Sydney, NSW, Australia

Gail V. Matthews

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Gail V. Matthews

Department of Infectious Diseases, St. Vincent's Hospital, Sydney, NSW, Australia

Anthony D. Kelleher

Kirby Institute, University of New South Wales (UNSW), Sydney, NSW, Australia

Anthony D. Kelleher

Department of Immunology, St Vincent's Hospital, Sydney, NSW, Australia

John J. Zaunders

NSW State Reference Laboratory for HIV, St. Vincent’s Centre for Applied Medical Research, Sydney, NSW, Australia