Alexandria Engineering Journal (Jan 2024)

Numerical investigation of a fractional model of a tumor-immune surveillance via Caputo operator

  • Saleh Alshammari,
  • Mohammad Alshammari,
  • Mohammed Alabedalhadi,
  • M. Mossa Al-Sawalha,
  • Mohammed Al-Smadi

Journal volume & issue
Vol. 86
pp. 525 – 536

Abstract

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Fractional calculus has become a potent tool for simulating the complexity of interactions in tumor-immune system dynamics. This paper investigates the existence and uniqueness of its approximation solutions of a fractional model of tumor-immune surveillance. This analysis is essential for proving the validity and dependability of the model and provides a more in-depth understanding of the dynamics of the tumor-immune surveillance system. Second, we examine the fractional model's numerical features. We utilize a numerical technique called the Laplace residual power series method to address the equations' complexity and nonlinearity. By defining the answers as a fractional power series, this method enables us to efficiently approximate the solutions. The use of this technique enables us to investigate the temporal evolution of the tumor-immune system, offering important insights into the stability and behavior of the system. We assess the effectiveness of the Laplace residual power series method in locating approximations through a series of thorough numerical simulations. To ensure the correctness and dependability of our method, we compare the numerical findings whenever possible with well-known analytical solutions.

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