Synthesis and Evaluation of Ivacaftor Derivatives with Reduced Lipophilicity

• Melissa Iazzi,
• Phillip Junor,
• Jitesh Doshi,
• Saujanya Acharya,
• Roxana Sühring,
• Russell D. Viirre,
• Gagan D. Gupta

Affiliations

Melissa Iazzi

Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario, Canada

Phillip Junor

Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario, Canada

Jitesh Doshi

Peptris Technologies, Centre for Cellular and Molecular Platforms, Bangalore, Karnataka, India

Saujanya Acharya

Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario, Canada

Roxana Sühring

Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario, Canada

Russell D. Viirre

Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario, Canada

Gagan D. Gupta

Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario, Canada