BOTULINUM TOXIN A FOR THE MANAGEMENT OF INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME

Abstract

Interstitial Cystitis/Bladder Pain Syndrome is a chronic and debilitating condition that negatively impacts quality of life. Several causes have been postulated in the pathogenesis of this condition; however, the etiology remains unknown. Interstitial сystitis may go undiagnosed for many years because the condition often co-exists with other chronic pain syndromes. Furthermore, the symptoms of Bladder Pain Syndrome vary considerably across patients, therefore no one treatment has shown to be consistently effective in providing relief. Thus, the goal of management of interstitial сystitis remains to provide relief of symptoms in order to improve a patient’s quality of life. intravesical Botulinum toxin A is emerging as a potential new pharmacologic treatment for interstitial сystitis refractory to conventional treatment modalities. The aim of our short review is to assess the efficacy of intravesical Botulinum toxin A in Bladder Pain Syndrome.

Keywords

• botulinum toxin
• bladder pain syndrome
• interstitial сystitis
• intravesical treatment