Communications Biology (Jan 2023)

Exploration driven by a medial preoptic circuit facilitates fear extinction in mice

  • Anna Shin,
  • Jia Ryoo,
  • Kwanhoo Shin,
  • Junesu Lee,
  • Seohui Bae,
  • Dae‐Gun Kim,
  • Sae-Geun Park,
  • Daesoo Kim

DOI
https://doi.org/10.1038/s42003-023-04442-9
Journal volume & issue
Vol. 6, no. 1
pp. 1 – 10

Abstract

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A circuit running from CamKIIα-positive neurons of the medial preoptic area to the ventral periaqueductal gray induces exploration of a fear-conditioned place and facilitates fear extinction in mice.