Emerging Infectious Diseases (Feb 2011)

Characteristics of Patients with Oseltamivir-Resistant Pandemic (H1N1) 2009, United States

  • Samuel B. Graitcer,
  • Larisa Gubareva,
  • Laurie Kamimoto,
  • Saumil Doshi,
  • Meredith Vandermeer,
  • Janice Louie,
  • Christine Waters,
  • Zack Moore,
  • Katrina Sleeman,
  • Margaret Okomo-Adhiambo,
  • Steven A. Marshall,
  • Kirsten St. George,
  • Chao-Yang Pan,
  • Jennifer M. LaPlante,
  • Alexander Klimov,
  • Alicia M. Fry

DOI
https://doi.org/10.3201/eid1702.101724
Journal volume & issue
Vol. 17, no. 2
pp. 255 – 257

Abstract

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During April 2009–June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant. Most patients with oseltamivir-resistant infections were severely immunocompromised (76%) and had received oseltamivir before specimen collection (89%). No evidence was found for community circulation of resistant viruses; only 4 (unlinked) patients had no oseltamivir exposure.

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