Рациональная фармакотерапия в кардиологии (Jan 2016)

FIXED LOW-DOSE COMBINATION OF LISINOPRIL AND HYDROCHLOROTHIAZIDE IN THE PREVENTION OF CARDIOVASCULAR EVENTS IN HYPERTENSIVE PATIENTS

  • A. O. Shevchenko,
  • O. P. Shevchenko

DOI
https://doi.org/10.20996/1819-6446-2010-6-5-697-702
Journal volume & issue
Vol. 6, no. 5
pp. 697 – 702

Abstract

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Peculiarities of the mode of action and clinical use of fixed low-dose combination of lisinopril and hydrochlorothiazide are discussed. Reasonability of ACE inhibitor and thiazide diuretic combination is supported due to more effective blood pressure control, organoprotection improvement and side events risk reduction. Results of the clinical studies on efficacy and safety of this combination in hypertensive patients with different concomitant diseases are presented.

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